HSP expression in bivalves

Authors

  • E Fabbri Interdepartment Centre for Environmental Science Research, University of Bologna, campus of Ravenna, Italy
  • P Valbonesi Interdepartment Centre for Environmental Science Research, University of Bologna, campus of Ravenna, Italy
  • S Franzellitti Interdepartment Centre for Environmental Science Research, University of Bologna, campus of Ravenna, Italy

Keywords:

bivalves, HSP, HSP expression, HSP phylogeny, HSP sequence, stress response

Abstract

One of the molecular responses which mostly contribute to the physiological plasticity of bivalves
is the heat shock response mediated by heat shock proteins (HSP). Variations of HSP response were
observed under environmental conditions, correlated with differences in environmental temperature
and degree of heterogeneity across geographic thermal gradients and through time. Laboratory
experiments characterized the expressions of different protein isoforms and coding genes, which are
induced by heat as a prototypical stimulus. Nevertheless, other physical and chemical factors
significantly induce HSP gene and protein expressions in bivalves, that can be different depending on
tissues and the nature of the insult. Multiple alignments of the deduced amino acid sequences
indicated that the bivalve HSP70 proteins share common structural and evolutionary features with the
mammalian HSP70, while some appear to be exclusive. The rate at which new findings are made
regarding the bivalve HSP response is still increasing. However, some major questions remain
unanswered. Among them, the possibility that the bivalve HSP response is related to cell signalling
pathways and acts as a component of the acute systemic response to stress is also discussed in this
review.

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Published

2008-09-26

Issue

Section

Review